New research has discovered that smoking and oral sex are tied to an increased risk of developing HPV-related oropharyngeal cancer, which is a form of head and neck cancer activated by exposure to the human papillomavirus (HPV).Although the risk is increased, it is still low; only 0.7 percent of men are ever likely developing oropharyngeal cancer during their lifetimes, according to the new study.The risk of developing the condition was found to be considerably lower among women, non-smokers, and those who had had fewer than five partners with whom they had performed oral sex.Prof. Gypsyamber D'Souza, of the Johns Hopkins Bloomberg School of Public Health, and Dr. Carole Fakhry, of the Johns Hopkins Department of Otolaryngology-Head and Neck Surgery — both of which are located in Baltimore, MD — conducted the research.
Their results have been published in the journal Annals of Oncology.Every year in the United States, there are approximately 16,500 cases of oropharyngeal squamous cell carcinoma, which is the most common type of oropharyngeal cancer. More than 11,500 of these are HPV-related.
More than 100 different types of HPV exist, but only a few of these are known to cause cancer. HPV16 or 18, for example, triggers most cases of cervical cancer, and HPV16 is known to cause most oropharyngeal cancers.
Experts have predicted that by 2020, the incidence of oropharyngeal cancer will overtake that of cervical cancer."For these reasons," says Prof. D'Souza, "it would be useful to be able to identify healthy people who are most at risk of developing oropharyngeal cancer in order to inform potential screening strategies, if effective screening tests could be developed."She adds, "Most people perform oral sex in their lives, and we found that oral infection with cancer-causing HPV was rare among women regardless of how many oral sex partners they had.""Among men who did not smoke," Prof. D'Souza says, "cancer-causing oral HPV was rare among everyone who had less than five oral sex partners, although the chances of having oral HPV infection did increase with number of oral sexual partners, and with smoking."The study data came from 13,089 individuals, all of whom were aged 20–69 years old, who took part in the National Health and Nutrition Examination Survey.The participants had all been tested for oral HPV infection. To predict the risk of oropharyngeal cancer from oral HPV infection, the researchers used data on oropharyngeal cancer cases and deaths from U.S. registries.
Smoking and oral sex partners elevate risk
Prof. D'Souza and Dr. Fakhry found the lowest prevalence of oral infection with cancer-causing forms of HPV in women who had had one or no oral sex partners during their lifetimes.
Of these, 1.8 percent were smokers and 0.5 percent were non-smokers. The risk of infection climbed slightly to 1.5 percent for women who had had two to more oral sex partners.
Among men, those who had had one or no oral sex partners were at the lowest risk, with a prevalence of 1.5 percent for oral HPV infection. Among men with two to four oral sex partners, prevalence increased to 4 percent among non-smokers and elevated further to 7.1 percent among men who smoked.
Non-smoking men who had had five or more oral sex partners had a prevalence of oral HPV infection of 7.4 percent. The highest prevalence of infection — reaching 15 percent — was observed among men with five or more oral sex partners and who smoked.
Continue reading.. Could oral sex raise your head and neck cancer risk? [...]
... Department of Public Health and Clinical Medicine at Umeå University in Umeå, Sweden. "A Paleolithic-type diet, high in polyunsaturated fatty acids, may have long-term beneficial effects on obesity-related disorders, including reduced risk for ... [...]
Dr. Freedland: PSA is a marker of prostate pathology. While often used to screen for prostate cancer, it is not prostate specific and can be elevated due to inflammation or enlarged prostate or other reasons. Whether it predicts the development of ... [...]
"Despite the higher prevalence and incidence, delay in diagnosis is a feature consistently reported, and as a result of delayed diagnosis they also have delayed treatment and have significant joint damage and disability at the time of diagnosis," she ... [...]
The risk of becoming infected with TB is increased by exposure to smoke from cigarettes and burning fuel. Now, a new study shows this is because smoke clogs up immune cells and weakens their ability to fight TB bacteria. Macrophages When normal ... [...]
Although a steady decrease began following the peak period, patients with cancer still experienced an elevated risk for mental disorders up to 10 years after receiving their diagnosis (HR = 1.1; 95% CI, 1.1-1.2). ... Having advanced or metastatic ... [...]
Prostate cancer radiotherapy treatment side effect Prostate cancer, one of the most common types of cancer in men, is often treated with radiotherapy, however, experts now believe that this form of treatment can lead to secondary cancers. Radiotherapy ... [...]
The men who ejaculated for at least 21 times a month when they were 20-29 were found to be 19 percent less likely to be diagnosed with prostate cancer compared to the guys who ejaculated for just seven times monthly, Huffington Post reported. Meanwhile ... [...]
Between 2002 and 2003 breast cancer rates decreased by 7%, most likely due to the decrease in use of hormone therapy in the form of estrogen and progestins (synthetic progesterone). “Hormone ... Very recent research shows that women can actually reduce ... [...]
“Ejaculation frequency is, to some extent, a measure of overall health status in that men at the very low end of ejaculation – 0 to 3 times per month – were more likely to have other (medical problems) and die prematurely from causes other than ... [...]
Pirates left-hander Tony Watson said the players would prefer not to go to Puerto Rico, "but we don't have all the facts, either. We're trying to walk a fine line here. It's an interesting situation that we're getting constant feedback from the CDC ... [...]
If abortion were not a politically protected procedure, there would be agreement based on the facts: abortion is a risk contributor for breast cancer. If women were given fair warning of the risks attributed to abortion — breast cancer being one of ... [...]