target

Two known chemotherapy agents effectively target breast cancer stem cells
Thangaraju's lab has evidence that the two additional drugs directly affect at least two key ways that enable stem cells to make breast cancer, including the myoepithelial cells that enable it to spread to the bone, lung and beyond. They appear to help ... [...]
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Treating to Target in Psoriatic Arthritis
Treating to target is becoming the standard of care in many medical specialities, including rheumatology. The Tight Control of Psoriatic Arthritis (TICOPA) trial has recently provided evidence of the benefit of treating to target in psoriatic arthritis ... [...]
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New target makes end run against therapy-resistant prostate cancer
Reducing AR levels could help patients overcome treatment-resistant prostate cancer and even rescue existing therapies. The research was published today in the prestigious journal Nature Medicine. “This is a new target and a totally new way of hitting ... [...]
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New target makes end run against therapy-resistant prostate cancer University …
Reducing AR levels could help patients overcome treatment-resistant prostate cancer and even rescue existing therapies. The research was published today in the prestigious journal Nature Medicine. "This is a new target and a totally new way of hitting ... [...]
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Rheumatoid Arthritis Research Indicates Serotonin Could Be New Target for …
Researchers have shown for the first time that serotonin plays a fundamental role in the pathology of rheumatoid arthritis, through the regulation of essential regulatory immune cells and cells responsible for bone re-absorption. The findings might ... [...]
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NI Health: Breast cancers diagnosed after target times breached in Belfast Trust
Earlier this month, figures from the Northern Ireland Cancer Registry showed a dramatic rise in the numbers of women being diagnosed with breast cancer, with an overall increase of 53% in the number of women being treated for the disease in the last 20 ... [...]
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Rheumatoid arthritis Could glucose metabolism be a sweet target for RA therapy?
... cells and abrogate arthritis in vivo. “We believe that targeting metabolic dysfunction offers a novel approach to understanding the mechanisms of disease, susceptibility to RA, and potential new treatment options,” reports corresponding author ... [...]
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MD Anderson Researchers Find Novel Therapeutic Target Against Aggressive …
“While a new treatment for triple-negative breast cancers would be a major advance, DAPK1 inhibitors have the potential to be used to treat many different kinds of cancers with TP53 mutations, which include the most lethal cancers without effective ... [...]
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New prostate cancer treatments could target metabolism
Our long-term goal is to develop new metabolic-based therapeutic approaches for the detection and treatment of prostate cancer." While the bulk of work is being done at the Center for Nuclear Receptors and Cell Signaling in UH's College of Natural ... [...]
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