Progression

Acute progression of recurrent meningioma during luteinizing hormone-releasing …
CASE DESCRIPTION - A 72-year-old man with benign meningioma underwent tumor resection and had no recurrence for 18 years. He was found to have prostate cancer and received hormonal therapy with a luteinizing hormone-releasing hormone (LHRH) ... [...]
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ROBO1 protein may delay progression of breast cancer
A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness" by ... [...]
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Common variation in BRCA1 may have a role in progression to lethal prostate …
BACKGROUND - To evaluate whether single-nucleotide polymorphisms (SNPs) reflecting common variation in the tumor suppressor BRCA1 affect prostate cancer outcomes. Because radiation therapy (RT) induces DNA damage, we hypothesized that ... [...]
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Factors predicting progression to castrate-resistant prostate cancer in …
This is pertinent as the Triptocare study did not show that urinary PCA3 score was a reliable marker of cancer stage in advanced prostate cancer and was not useful for assessing response 6 months after initiation of androgen deprivation therapy (ADT ... [...]
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Diet-induced alteration of fatty acid synthase in prostate cancer progression
A high-fat diet (HFD) is attributed to prostate cancer (PCa) progression, but the role FASN on HFD-mediated PCa progression remains unclear. We investigated the role of FASN on PCa progression in LNCaP xenograft mice fed with HFD or low-fat diet (LFD), ... [...]
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DNA Damage, Repair Profiling a Biomarker of PCa Progression
A newly developed profiling method may be helpful in the management of patients with high-risk prostate cancer. Investigators have created a DNA damage and repair (DDR) pathway profiling method that may be used in the management of patients with ... [...]
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